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Zinc finger inhibitors, or zinc ejectors, are substances or compounds that interact adversely with zinc fingers and cause them to release their zinc from its binding site, disrupting the conformation of the polypeptide chain and rendering the zinc fingers ineffective, thereby preventing them from performing their ...
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Preclinical evaluation of a zinc finger inhibitor targeting lentivirus nucleocapsid protein in SIV-infected monkeys · Authors · Affiliation.
Zinc finger inhibitor for HIV. Treat Rev. 1996 Dec:(No 23):13. PMID: 11364280. Abstract. AIDS: Zinc finger inhibitors are a class of anti-HIV drugs currently ...
Our previous findings with the zinc finger inhibitor NOBA. (45, 46) demonstrated that the zinc-coordinating cysteine thio- lates of the retroviral zinc ...
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Jul 1, 2006 · Preclinical Evaluation of a Zinc Finger Inhibitor Targeting Lentivirus Nucleocapsid Protein in SIV-Infected Monkeys ... Keywords: HIV/SIV; NCp7; ...
The compound azodicarbonamide (Azo) was investigated as another E6 zinc finger inhibitor that targets Cys-Cys-His-Cys zinc finger domains of the nucleocapsid p7 ...